I've never liked a .410 for most game shooting....I prefer #5 shot for squirrels, and you don't get a lot of those packed in a .410 shell, including the 3" hull. Plus, most of the squirrels I have run across have some tough skin....I find a lot of pellets lodged just under the skin.....I hate the thought of a wounded critter getting away and dying a slow, miserable death. I would think that a 20 gauge, loaded with 1 oz of shot or more, would be sufficient. I don't have any experience with the 28 bore, but I think it would be too light for squirrels as well.
Tradition has it that most youngsters took thier first game (rabbit, squirrel) with a .410......but I don't stand on tradition!