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Skeet is correct. It is very dangerous to fire a .22LR in a .22 WMR barrel, and it would be equally foolhardy to attempt to fire a 17 Mach II in a 17 HMR barrel.
Both of the longer magnum-based catridges have a larger rim diameter and a larger case diameter. The shorter round will literally rattle in the magnum chamber. The smaller round almost always ruptures, either at the rim or down the length of the case - or both. Hot gas, burning powder and brass fragments exit the gun in most instances.
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