[Mickey Rat]

The best thing to have is whatever you got. I think a 357 is a bit too noisy, but that's just me.

A Ruger 10-22 is a great home defense gun. Not scary to shoot-even for the wife, cheap to practice with, and most folks can point shoot it pretty good. 10 22 rounds in about 2 seconds is pretty impressive.

A 410 or 20 guage are both good home defense guns. Either will provide a one shot stop, and both are inexpensive and easier for most people to handle.

Remember, nobody wants to get shot, even a little bit.