I have both.
FRankly, if I were planning on doing a lot of shooting witht he most potent of loads, I'd go the Redhawk, period! My S&W is an early 629 that literally has to be rebuilt after about 250 serious rounds. Now before the flame pop up to engulf me, I understand S&W has made changes to the internal lock works to correct the problem, although it took them long enough to do so.
I hike in serious black bear country, serious because the local isiots feed them and they're very accustomed to humans and sometimes get a little ticked off if you don't feed them.
The S&W now is relgated to light .44 Spl. grade loads for targets and the Redhawks are on call for serious duty, should that become necessary.
Paul B.