If it were my gun, I'd be looking at a premium or near-premium bullet in the 180-200 grain area.
Premium bullets are almost required in mega-magnums, but the 300 Winnie is a bit less critical, so a semi-premium like an interlock or hot-core bullet should be fine. If there's a chance at a spitting distance shot, though, I'd lean toward a genuine premium bullet to avoid blowup at short range/high velocity.
Your reloads are the cheapest part of the hunt, so don't scrimp on bullet quality. The whole hunt can depend on just one of them.
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