I load for the .45 Colt. A couple years ago I came across a stout load from a well maker of stout loads. I loaded some up for my Ruger. Before I could shoot them I posted about it on here. Rocky and some others had misgivings about the "starting" load. So I loaded up some rounds working up to this "starting" load. Go thing I did. I quit before I made it all the way up. I'm not averse to to recoil in a handgun, but they were plenty uncomfortable to shoot. Not that I think the gun would have gone kaboom, I'm not sure if I could have kept the hammer from seeking a resting place in my forehead.
Seems the rage today is to push the .45 waaay past the .44 mag. It can best the .44 but always use caution and prudence.