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I ran three very common rifle loads through my copy of Oehler Ballistic Explorer. Here are the drop tables that came out:
Cartridge 50 yds 100 150 200 250 300 350 400 450 500
.243 100 gr 1.1 2.6 2.9 12.0 -0.5 -4.5 -10.3 -18.0 -28.0 -40.5
.270 140 gr 1.1 2.6 3.0 2.0 0.0 -4.3 -10.0 -17.5 -27.0 -39.0
.30-06 180 gr 1.1 2.7 2.9 1.8 -0.8 -5.1 -11.2 -19.5 -30.0 -43.0
That may be a bit hard to read, but if you compare columns, you see that with a sight-in of about 2.7 inches at 100, all three loads stay within six inches of the aimpoint out to 300 yards. The highest rise above aimpoint is just over three inches at about 155 yards. From the muzzle to 300 yards, you could hold at "center of deer" with any of the three cartridges.
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