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Once you throw moose and bear into the equation, penetration and bullet strength follow along.
The 180 Nosler Partition is still the bullet to which all others are compared, and it's never a bad choice. Earlier versions were sometimes not as accurate due to the difficulty in making the bullet, but they solved that some time ago. Today's Partition is a superb bullet.
Another option would be to drop back one weight slot and use the 165 Barnes TSX. It penetrates as well as a heavier bullet, is very accurate and will offer you a bit more speed and a bit less recoil due to its lower weight.
I don't load for the 30-06 but in the 308, I like either RL-15 or W760 powders.
With the 165 TSX Barnes bullet, try 41.0 to 45.0 of RL-15 OR 46.0 to 50.0 of W760 for right at 2800 fps. (Both loads from the Barnes manual.)
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