It depends on what you mean.
The current barrels are compatible with all early frames (but not all early barrels will work with new frames - hope that's not confusing) Simple explanation: new barrels are fine.
There can occassionally be a slight misfit between a barrel and a frame, due to the size of the mounting pin hole. The pins can also be off-size. There are three/four points where tolerances can be off: the barrel hole, the pin, and the two frame holes.
For the best accuracy, they should all fit snugly. The holes can be polished to the same size, and a pin can be ground (or bought oversize) if your barrel(s) and frame don't match up.
But there is no across-the-board fit problem that I'm aware of.
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