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fabsroman............... the .25-06 is a great cartridge, I like it a lot. With the new bullets, such as the 100 and 115 grain Barnes TSX and the 110 Nosler Accubond it can do a lot with light to medium sized big game.
I have used it to take Mule deer, whitetail, elk, moose, black bear, etc. No I do not recommend it for elk or moose. I was deer hunting and had it in my hands along with a tag each time. But, with a good bullet and proper shot placement it will do the job.
For deer I would not hesitate to use it out to about 350 or 400 yards, as I have done so a number of times. Even on these big Canadian whitetails and mule deer they never went more than a few yards if they didn't drop in their tracks.
As for varmints. Well I usually use a .222 Rem. When the distance gets past 200 yards on coyotes and such, or the wind gets blowing, I switch to the .25-06. I use the same TSX and Nosler bullets. Little hide damage and good practice with the big game loads. I wouldn't use it on small stuff like marmots.....too expensive, but I have used the 87 grain Sierras in the past for that and they worked well.
I like the .25-06. It kills really well, ever bit as good as a .270, and I have killed a lot of game with it as well over the years.
For real long range work in a .25 check out Wildcat Bullets. The owner produces .25 grain bullets up to 150 grains and these are LONG bullets.
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