Set-up time depends on what round your changeing from and to. If you are changeing from .243 to .30-06 al that is required is to change the tool head and the powder measure, 2 mins. tops. If your changeing from 06 to .357 mag. , then you have to also change the priming tube and the shell holder. Even the long cannges only take about 5 min. once the tool heads are set up. I`ve been loading on a 550 since the 70`s and still think it`s better than sliced bread.