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I've never loaded the .380, but I reload a lot for the almost identical 9 Makarov. You might check out my old article on it at reloadingroom.com keeping in mind that the two cartridges are not identical. Reduce my top charges by 10% and you should be fine.
I had excellent luck with a variety of powders, including Unique, RedDot, American Select, Clays, Universal Clays, Green Dot, 700X and several more.
I have an old article (not by me) about powders that says the best powder for the .380 is the very old and almost completely overlooked IMR PB. If you want to try some PB, I'll look up the article for data.
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