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I rather doubt it. There just isn't enough case volume with the bullet seated.
Trailboss is an extremely "fluffy" powder - it was developed to take up most of the otherwise empty volume in big cases, yet give light loads for Cowboy Action shooting. It takes a case-full in a 45 Colt to generate 800 fps or so with 200 gr bullets. So there certainly wouldn't be enough room for it in a .45 ACP with the same bullet.
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