GOB, I have a 357 and used to use with 38special Hydroshoks for close range groundhogs.
I winged one at distance with the 22-250 and the chuck made it to its hole.
Walked up and was going to finish it off with the wheelgun.
After absorbing a couple of shots I was down to two in the cylinder and the bugger came up after me from the hole.
Killed it with my final round. Thought I was going to have to throw the durn gun at it...
From then on I save 38's for the range and use 357 mag loads for critters and bad guys. I know that an animal is different than a person but this is just my opinion.
Hey, what happened to getting an XD-45acp?