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I would use:
220's for moose
180's for elk
165's for mule deer
150-165 for whitetail
I might add that my actual experience is limited to whitetails. I prefer 165's in the '06 for general use. The Sierra 165 expands readily, makes a huge exit, and nails whitetails on the spot with any kind of decent hit.
For a 600 lb.elk or a 1500 lb. moose using an '06, a Nosler partition would be in order for me.
Rev
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