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I use 180 grain Hornady's in my 30-06 for deer. If I were limited to a 30-06 for elk (I am not) I would go to the 180 grain Nosler Partition. They shoot to the same point of impact and they both shoot great.
If I were to go after Moose and I have not, I would do some penetration testing to see if perhaps a 200 grain bullet might penetrate better. -- I love Partitions for big game.
BTW, My brother in law used 165 grain Sierras in his 300 Win Mag and followed the wounded elk all day and eventually lost it. But then I don't like Sierras for bug game unless it is much heavier than normal diameter weight etc. than other bullets. T o me they are comparable to ballistic tips.
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