I don't see any reason why you
couldn't, but I can think of a few reasons why I
wouldn't want to carry a single action revolver for CCW. The first is probably the obvious...having to cock the firearm manually each time to fire. That's a handicap that I don't think I want to give an opponent in a firefight, even if he is similarly armed. The second reason is the impression it will give to said prosecuter if I am in said firefight...the illusion that I am a 'cowboy' looking for a 'gunfight at the O.K. corral'. Probably not an issue in Texas (hell, probably a REQUIREMENT!

), but here in liberal Michigan you can bet it will be used to paint as negative a picture as possible.
Now, having said that, I do open carry while hunting/fishing with my .357 Vaquero....I like the gun, it draws easy from a hip holster, and (don't tell anyone this...not even my wife!), I've always
wanted to be a cowboy since I was 5 years old....even got the hat and boots and everything!
Finally, I think you might have some trouble finding concealment leather for a single action, colt style revolver....but I can't say for certain; I haven't looked.