I used a 270 on Caribou with a favorite load of the Hornady 130 gr SP inter-lok and R22. I dropped 2 boo, one took a broadside that clipped a rib going in and took a piece of off side shoulder blade exiting and the other animal I hit through the ribs, and because he stood dead on his feet faceing me, put a second bullet throught the neck severing the spine at the hump. All shots were from ~ 100yd - 150yd and all bullets passed through. A buddy of mine took only his bow and on the last day of the hunt borrowed my rifle and dropped a boo with two quick rounds through the ribs, again all exited at around 75 yds.
Velocity in my rifle ran around 3000 fps with a 24" BBL and accuracy was under 1 moa. I presently have another 270 Win with a 26" LW barrel that also likes this load. There are a bullet or two that are a hair more accurate, but as far as accuracy and velocity go R22 still does very well. The Hornady bullet is geat for deer, and I found it exellent on caribou, fast opening and it penitrates very well for a inexpensive choice. ( all boo were, I`d guess, about 275 lbs live. Average mature animals)
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