If you could have just one powder......

[Evan03]

h4831sc
covers the 2506 220 3006 270 22/250 the 22hornet throughs a curve in there ill just get rid of that caliber

right now i have about 8 powders on the bench and each calibers seems to prefer something difrent

[Gil Martin]

I agree with Unique for handguns and shotguns and IMR4895 for rifles. All the best...
Gil

[Seawolf1090]

Having tried Unique in three different pistol calibers and been very disappointed, I now use Bullseye almost exclusively - the exceptions being Lil Gun for .22 Hornet and .357 Magnum.
RedDot is my Number Two 'go to' powder. My smallest pistol caliber is 7.62 Nagant, the largest is .45ACP. Either powder does them all.

For rifles, I am currently really liking Ramshot's TAC. Loads nearly all my rifle calibers. For the milsurps, I still prefer the IMR4895 though. Some 'odder' milsurp calibers don't have data yet for the TAC powder.