I've had the misfortune of only owning 
ONE .22 rimfire handgun....a standard model Ruger MkII that I modified slightly by putting wood grips and Millet target sights on it.  The gun fits nicely in an old Walther P-38 holster (copy).  I remember when I first became interested in firearms, there were a LOT of choices out there: H & R, Ruger, Colt, High Standard, ect.  Doesn't seem to be the variety out there today that there use to be.
  Anyway, whaddayagot?

  I always liked the look of the Colt Woodsman, and the S&W line was nice as well.  Always wanted (but never got

) the Ruger Single Six combo with the two cylinders; one for .22LR and the other for .22 magnum.