While I have mixed feelings about this shot, I've done it before. Two years ago my brother and I both killed our bucks with hard quartering toward shots. Range was close (my brother took his buck at 5 yards). The best is a slight angle. Just hold right inside the front shoulder, and you should get an exit at the back of the ribcage on the other side. The most important part of this is be extremely judicious about shot angle and range. 15 or 20 yards should be a maximum. JMHO
We hunt, not only because we want to, but because at our basest levels we must.